FANGYIN MENG, MD, Ph.D
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Recurrent Pregnancy Loss and Balanced Translocation

When miscarriages repeat, we look for treatable causes. One important genetic factor is balanced translocation, which can increase the chance of embryos being chromosomally unbalanced. When to consider testing Consider parental karyotyping if you have: What the results mean A balanced translocation in a parent does not automatically mean a poor prognosis. The exact risk […]

Balanced Translocation and IVF

A balanced translocation is a chromosomal rearrangement where pieces of two chromosomes swap places without a net gain or loss of genetic material. Many carriers are healthy and may never know they carry it—until they face infertility, recurrent miscarriage, or repeated embryo implantation failure. Why can a “balanced” change affect fertility? Even when the carrier […]