When miscarriages repeat, we look for treatable causes. One important genetic factor is balanced translocation, which can increase the chance of embryos being chromosomally unbalanced.
When to consider testing
Consider parental karyotyping if you have:
- two or more miscarriages,
- repeated early pregnancy losses,
- or a prior abnormal pregnancy genetic test.
What the results mean
A balanced translocation in a parent does not automatically mean a poor prognosis. The exact risk depends on:
- which chromosomes are involved,
- the size of exchanged segments,
- and prior pregnancy history.
IVF pathway
IVF with PGT-SR can help identify embryos more likely to lead to an ongoing pregnancy. For some couples, it can reduce time-to-pregnancy by lowering miscarriage risk.
FAQ
- Can we conceive naturally after miscarriages? Many do; the decision depends on age, history, and priorities.
- Does PGT-SR guarantee success? No—but it can improve selection.
CTA: Book a consult for a miscarriage workup + genetic plan.