What is Mini Stim IVF?

Mini Stim IVF is a form of in-vitro fertilization that uses lower doses of injectable medications combined with oral medications to stimulate the ovaries.
The goal is to produce fewer, but higher-quality eggs while reducing medication side effects and treatment costs.
It is especially helpful for patients who have a limited antral follicle count (AFC).

You will benefit more from mini IVF if you have low ovarian reserve.

Who May Benefit from Mini Stim IVF

  • Women with low ovarian reserve (low AFC or AMH)
  • Women of advanced reproductive age
  • Patients who want to reduce medication costs
  • Patients who have poor response to high-dose stimulation in previous IVF cycles
  • Those wishing to avoid high hormone exposure and related side effects

Types of Mini Stim IVF

  • Natural Cycle IVF
    • No stimulation medications, only monitoring the natural cycle and retrieving the egg that develops naturally.
  • Minimal Stimulation IVF
    • Combination of oral medications (e.g., clomiphene, letrozole) and low-dose injectable gonadotropins to encourage the growth of a small number of eggs.

Treatment Process

  1. Ovarian Stimulation – Low-dose injections + oral medications to promote egg growth.
  2. Monitoring – Ultrasound and/or blood tests to check follicle development.
  3. Trigger Shot – hCG injection to mature the eggs.
  4. Egg Retrieval – Collection of eggs under light sedation.
  5. Fertilization & Embryo Culture – Eggs are fertilized and monitored in the lab.
  6. Embryo Transfer or Freezing – Best-quality embryo(s) are transferred to the uterus or frozen for future use.