A karyotype is a chromosome analysis that can identify balanced translocations, Robertsonian translocations, and other large rearrangements.
Who should consider a karyotype?
- recurrent miscarriage
- infertility without clear cause
- repeated IVF failure
- prior pregnancy with chromosomal abnormality
- family history of translocations
What a karyotype can (and can’t) tell you
It can identify large structural changes and define a carrier state. It may not detect small CNVs; CMA may be added when clinically indicated.
How results change the treatment plan
A confirmed translocation often prompts discussion of:
- IVF with PGT-SR,
- counseling on natural conception vs IVF,
- and prenatal testing strategy once pregnant.
FAQ
- Do both partners need testing? Often yes in recurrent loss or unexplained infertility.
- How long do results take? Timing varies by lab.
CTA: If you have repeated losses, ask for karyotype-based reproductive risk assessment.