What is Intrauterine Insemination?

Intrauterine insemination (IUI) is a simple fertility procedure in which washed and concentrated sperm are placed directly into the uterus, bringing them closer to the egg and increasing the chance of fertilization.

Who May Benefit from Intrauterine Insemination

  • Women with unexplained infertility
  • Women with irregular ovulation (e.g., PCOS)
  • Couples with mild male factor infertility
  • Single women or same-sex female couples using donor sperm

How Intrauterine Insemination Works

  1. Ovulation Monitoring – Ultrasound and/or hormone tests determine the best time for insemination.
  2. Sperm Preparation – Sperm from the partner or donor is washed and concentrated to select the healthiest ones.
  3. Insemination – A thin catheter is used to place the sperm directly into the uterus.
  4. Pregnancy Testing – About two weeks later, a blood or urine test confirms pregnancy.

Advantages of Intrauterine Insemination

  • Quick and minimally invasive
  • No anesthesia required
  • Lower cost than IVF
  • Can be repeated for multiple cycles

Types of Intrauterine Insemination

By Sperm SourceDescriptionIdeal For
Partner IUI (AIH)
Uses sperm from the female partner’s husband/partner, washed and concentrated before insemination.Couples where the male partner has healthy or mildly compromised sperm.
Donor IUI (AID)
Uses sperm from a screened donor, washed and concentrated before insemination.Single women, female same-sex couples, or couples with severe male infertility.

By Ovulation MethodDescriptionAdvantagesConsiderations
Natural Cycle IUI
Performed during a woman’s natural ovulation cycle without fertility drugs.Lower cost, minimal medication.Fewer eggs released, lower per-cycle success rate.
Stimulated Cycle IUI
Uses fertility drugs (oral or injectable) to stimulate ovulation before insemination.Higher chance of multiple eggs, potentially higher success rates.Risk of multiple pregnancy and ovarian hyperstimulation (OHSS).