Partial trisomy means an embryo has an extra copy of part of a chromosome, while partial monosomy means a missing part. These often occur together when a translocation segregates unevenly.
Why they matter in IVF
Embryos with segmental gains/losses may:
- arrest in development,
- fail to implant,
- miscarry,
- or progress with medical/developmental issues.
How testing helps
- CMA can detect segmental duplication/deletion.
- PGT-SR can reduce transferring embryos with known segmental imbalance patterns from a parental rearrangement.
FAQ
- Is partial trisomy the same as Down syndrome? Down syndrome is full or mosaic trisomy 21; partial trisomy refers to a segment.
- Do all segmental changes cause severe issues? Not always—clinical impact varies.
CTA: Our team can match testing to your history and results to guide safe next steps.